- New stuff to read and discuss
- What patients say
- Clinic / online appointments
- Why the diagnosis of a psychosomatic illness is often a misdiagnosis
- Vascular Compression Syndromes
- Do you have questions?
- Checklist vascular compression syndromes
- Description of your symptoms
- Researchers from the Mayo Clinic confirm my concept of the Midline Congestion Syndrome
- Musculoskeletal pecularities of female puberty
- Lordosis /Swayback- Origin of many abdominal compression syndromes
- Nutcracker-Syndrome is a misnomer! Lordogenetic left renal vein compression is a more appropriate name!
- May-Thurner-constellation (May-Thurner-syndrome, Cockett’s syndrome)
- Midline (congestion) syndrome
- Pelvic congestion syndrome
- Celiac Trunk Compression / Dunbar syndrome / MALS / Arcuate ligament syndrome
- Wilkie-Syndrome / Superior-mesenteric-artery-syndrome
- Evlauation of vascular compressions with the PixelFlux-method
- Connective tissue disorders predispose to multiple compressions
- Postural tachycardia syndrome (POTS) – the hemodynamic consequence of vascular compression syndromes and loose connective tissue
- Restless legs-a little known symptom of abdominal vascular compression syndromes
- Pudendal neuralgia in vascular compression syndromes
- Migraine and Multiple Sclerosis
- Treatment of vascular compression syndromes
- Fatal errors in the treatment of vascular compression syndromes
- Risks of stents in venous compression syndromes
- Surgical treatment of abdominal compression syndromes: The significance of hypermobility‐related disorders
- Nutcracker and May-Thurner syndrome: Decompression by extra venous tube grafting and significance of hypermobility related disorders
- Our surgical treatment of vascular compressions
- Vascular compression syndromes I recently detected
- Detection of a new compression syndrome : Bilateral compression of the internal iliac vein between the psoas muscle and the internal iliac artery in a patient with chronic penile pain
- Diaphragmatic compression of the hepatic veins – a novel compression syndrome
- Post-prandial pain in the right upper abdomen due to a newly detected compression syndrome of the right renal vein
- A new sonographic sign of severe orthostatic venous pooling
- Gradually increasing, unbearable pain in the left flank only when standing or sitting – first description of a new compression syndrome
- A rare variant of Wilkie syndrome
- Kaleidoscope of instructive cases
- POTS – different from what you might think: an example
- Severe ataxia in a young woman with severe spinal congestion – complete resolution after decompression of the left renal vein
- Enigma resolved: vomiting during hip stretching
- Swollen bluish feet nausea unbearable epigastric and breast pain plus breathlessness
- Muscle cramps caused by a posture dependent pubic compression of the femoral artery
- Unbearable orthostatic pain in the autotransplanted left kidney
- Unbearable abdominal pain only while standing – easily diagnosed with PixelFlux
- Gradually increasing, unbearable pain in the left flank only when standing or sitting – first description of a new compression syndrome
- Abdominal pain due to liver compression in slipping rib syndrome in an EDS patient
- Genital and sexual symptoms of vascular compression syndromes – patient with ulcer of labia minora
- Posture dependent left flank / thoracic / lumbar pain – a new compression syndrome I recently detected
- Posture dependent unbearable breathlessness and fullness in the right upper abdomen due to a variable diaphragmatic compression of the hepatic veins and the vena cava inferior
- Migraines may develop in the wake of vascular compression syndromes
- Diaphragmatic compression of the liver veins with hepatic and intestinalis congestion
- Ultrasound Diagnostics
- Profile
- Functional colour Doppler ultrasound – how I do it
- Perfusion Measurement – PixelFlux-method
- Research
- Publications
- Nutcracker and May-Thurner syndrome: Decompression by extra venous tube grafting and significance of hypermobility related disorders
- Papers authored by Th. Scholbach
- Publications
- Inauguration of measurements of the tissue pulsatility index in renal transplants
- From nutcracker phenomenon to midline congestion syndrome and its treatment with aspirin
- First sonographic tissue perfusion measurement in renal transplants
- First sonographic bowel wall perfusion measurement in Crohn disease
- First sonographic renal tissue perfuison measurement
- First sonographic measurement of renal perfusion loss in diabetes mellitus
- PixelFlux measurements of renal tissue perfusion
- Why I prefer not to publish in journals but in the Internet
- Vessel stretching in nephroptosis – an important driver of complaints
- Publications
- Expertise
- Bornavirus Infection
- Scientific cooperation
- Cookie Policy
- Language:
- Cookie Policy (EU)
New stuff to read and discuss
2024 03 02
Our talk at the American Venous Forum, Tampa USA, March 2024
2024 01 20
A rare variant of Wilkie syndrome
(published on 20.01.2024 on the 41st birthday of Prof. Dr. rer. nat. Jakob Scholbach, who developed the first version of the PixelFlux software as a pupil at the Ostwald-Gymnasium in Leipzig)
2024 01 19
The problem of angle measurement in Wilkie syndrome
2024 01 17
PixelFlux is the most sensitive parameter to detect COVID related damage of the microvessels:
Our results show a significant association between the severity of respiratory failure and the impairment of peripheral and organ perfusion, which seems to be consistent with the pathophysiology of the development of ARDS. The usefulness of DTPM developed by Scholbach was investigated in many clinical applications [39,40,41,43,44]. Lubas et al. proved its usefulness in the assessment of renal perfusion among patients with hypertension and glomerulonephritis. However, DTPM was never investigated in ARDS or septic patients.
“revealed that the RCP [ PixelFlux measurements of renal cortical perfusion (inserted by Th. Scholbach) was the best independent parameter associated with the Oxygenation Ratio (R2 = 0.120; p < 0.001) (Table 7).”
“In the presented study, impaired kidney perfusion (RCP) correlates with the deterioration of gas exchange (Oxygenation Ratio; p < 0.000035 and CT score; p = 0.01).
Moreover, statistically significant associations concerning the relationship between the severity of ARDS and renal cortex perfusion, RCP, (p < 0.0001) were revealed. Nevertheless, according to the stepwise retrograde multivariable regression analysis, RCP was the best independent parameter linked to the Oxygenation Ratio.
Our results also show a correlation between the RCP and urea concentration (p = 0.031), which is consistent with the view of reduced renal flow and impaired renal function in sepsis [41,58]. Existing studies show a decrease in the blood flow through the cortex and medulla of the kidneys in patients with severe COVID-19, visible on magnetic resonance imaging [61].”
“It turns out that the peripheral perfusion parameters FIT (p = 0.038), CRT (p < 0.0006), RCP (p < 0.0002)[the best correlation of all parameters! – inserted by Th.Scholbach], and saturation (p = 0.0021) are better related to the severity of gas exchange than the pressure assessment, MAP, SBP, and DBP (p = 0.683, p = 0.718, and p = 0.474, respectively) (Table 5).”
“only renal cortex perfusion (RCP) was substantially correlated with the CT score (p < 0.010) …(CT score—based on Computer Tomography lung involvement severity score).”
“Dear Professor Scholbach,
…Your brilliant software still works! 😊
Kind regards,
Arkadiusz Lubas”
2024 01 17
Restless legs-a little known symptom of abdominal vascular compression syndromes
2024 01 13
POTS – different from what you might think: an example
2024 01 05
2023 12 23
Why the diagnosis of a psychosomatic illness is often a misdiagnosis
2023 12 15
Our chapter
appeared in
2023 11 30
Diaphragmatic compression of the liver veins with hepatic and intestinalis congestion
2023 11 30
I proudly annonce the first method ever for a 4D – blood flow volume measurement
2023 11 11
This paper: Non-Contrast Ultrasound Image Analysis for Spatial and Temporal Distribution of Blood Flow After Spinal Cord Injury (issued 09 Oct, 2023) confirms that the PixelFlux algorithm measuring area related blood flow intenity is the most sensitive ultrasound parameter to describe spinal cord perfusion.
2023 10 27
2023 10 26
Migraines may develop in the wake of vascular compression syndromes
2023 10 26
Researchers from the prestigious Harvard University publish the first paper on the application of our PixelFlux-software in stomatology!
PixelFlux has proven its usefulness in diagnosing stomatological issues after teeth implantation.
After my congratulation the author wrote:
“Your software is truly amazing. Thank you for this amazing contribution you gave to science
Lorenzo”
2023 09 26
2023 09 23
Our contribution to the American Venous Forum in Tampa, USA 3.-6. March 2024
My talks at the Annual German Angiological Conference in Leipzig 21.- 23.10.2023
52. Jahrestagung der Deutschen Gesellschaft für Angiologie – Gesellschaft für Gefäßmedizin e. V.
here search for “Scholbach”
Venous stenting of abdominal compression syndromes (ACS)- basically not a good idea – slightly extended talk at the DGA Conference 2023 in Leipzig
The lordogenetic midline syndrome – pathophysiology, diagnosis and treatment – talk at the DGA Conference 2023 in Leipzig
2023 08 08
2023 07 07
Genital and sexual symptoms of vascular compression syndromes – patient with ulcer of labia minora
2023 07 05
Abdominal pain due to liver compression in slipping rib syndrome in an EDS patient
2023 06 05
Commissioning of the new ultrasound system Philips Epiq Elite with 4D color cardiac and abdominal Doppler
2023 06 15
2023 06 08
Unbearable abdominal pain only while standing – easily diagnosed with PixelFlux
2023 05 07
Downloadable excerpt of my diagnostic spectrum
Excerpt from my diagnostic spectrum2023 03 30
Our paper
was among the most downloaded ones in the American Journal of Medical Genetics
I’m deeply thankful to my senior coauthor Professor Wilhelm Sandmann and coauthor Konstantinos Verginis and daily many hundreds of readers of my website
2023 03 22
The first paper comparing PixelFlux and conventional Doppler flow volume measurements of the portal vein show promising results with
apparently higher sensitivity of PixelFlux (left) for postprandial volume flow changes
Quantification of Portal Vein Vascularization Using an Automated PostProcessing Video Analysis Tool
2023 03 11
Neurological consequences of the spinal congestion in midline congestion syndrome
2023 02 16
Our contribution to the American Venous Forum 22-25.02.2023 San Antonio, Texas /USA : “Nutcracker and May-Thurner syndrome: Decompression by extra venous tube grafting and significance of hypermobility related disorders” Sandmann /Scholbach/Jacobi
2022 09 23
die rechtsseitige Rückenschmerzen und Schmerzen im rechten Ober- oder Mittelbauch verursachen
Zwerchfellkompression der Lebervenen – ein neues Kompressionssyndrom
verursacht intermittierende Schwellungen der Leber, Völlegefühl und Schmerzen im rechten Oberbauch
2022 09 11
Liste der Genitalsymptome bei Kompressionssyndromen in “Checkliste” eingefügt
2022 05 09
PixelFlux is recommended in diagnosis of Carpal Tunnel syndrome
chart from the above mentioned paper; inset by Thomas Scholbach
The authors refer to a very positive review of PixelFlux in the World Journal of Radiology 2020
” Interestingly, in the haemodialysis cohort, blood flow measurements were significantly improved after dialysis, suggesting that this measure may have future utility as a biomarker of both disease severity and treatment response[50]. Carroll AS, Simon NG. Current and future applications of ultrasound imaging in peripheral nerve disorders. World J Radiol 2020; 12(6): 101-129 [PMID: 32742576 DOI: 10.4329/wjr.v12.i6.101]”
2022 05 05
Project “International scholarship for quantitative functional color Doppler ultrasound training”
2022 04 10
Example of failed renal autotransplantation in left renal vein compression – the reasons why
2022 04 02
Addition to Wilkie syndrome page with example videos of patients with apparent duodenal compression that can be confidently classified as normal findings by functional sonography
2022 02 19
I now offer my papers for download for personal non-commercial use
Papers authored by others: by clicking this button I declare the only non-commercial use of this download
2022 02 15 (On occasion of the 88th birthday – 15.02.1934 – of my mother
Dr. med. Lilli Scholbach – ophthalmologist til her 75th birthday)
PixelFlux discriminates diabetic neuropathy in patients with chronic renal failure
Peripheral nerve morphology and intraneural blood flow in chronic kidney disease with and without diabetes
T Issar, S Walker, R Arnold, AM Poynten, ZH Endre… – Muscle & Nerve
2022 01 20 ( On occasion of the 39th birthday of my son Prof. Dr. rer. nat. Jakob Scholbach, developer of PixelFlux-software)
Under false flag – the so-called nutcracker syndrome Journal: Vascular Surgery
2022 01 04
Massive hematuria never in the morning but always in the evening – only PixelFlux knows the answer
2022 01 01 ( for the birthday of my great-grandfather Traugott Scholbach 01.01.1866 – 31.05.1942)
I added a search line on the top of all webpages – hoping to provide you more focused information from the dispersed and steadily growing content 🙂
2021 12 29
PixelFlux demonstrates rapid post-dialysis improvement of peripheral nerve perfusion ( BORIRE et al. Prince of Wales Clinical School, University of New South Wales, Sydney, Australia) :
“… we have shown that peripheral nerve hypervascularity is demonstrable in ESKD patients and rapidly improves following a single session of dialysis. Increased INBF is more likely to be seen in nerves of patients with evidence of axonal loss and moderate to severe neuropathy, suggesting that it may be a potential marker of neuropathy severity.
PixelFlux has significantly higher intra- and interobserver reliability than traditional methods to evaluate intraneural blood flow in carpal tunnel syndrome ( BORIRE et al. Prince of Wales Clinical School, University of New South Wales, Sydney, Australia)
PixelFlux perfusion measurements in peripheral diabetic nerves correlate significantly with the severity of diabetic neuropathy ( BORIRE et al. Prince of Wales Clinical School, University of New South Wales, Sydney, Australia)
2021 12 28
THE SURPRISING FREQUENCY OF HYPERMOBILE EHLERS-DANLOS (hEDS) AMONG PATIENTS WITH ABDOMINAL AND PELVIC COMPRESSION SYNDROMES (APCS) by W. Sandmann , K. Verginis, S. Jacobi, and T. Scholbach
Hyper-elastic fibrous tissue disorder is a risk factor for development of multiple retroperitoneal and pelvic compression syndromes and for recurrences after surgery by W. Sandmann , K. Verginis, S. Jacobi, and T. Scholbach
EDS COMPLICATED BY SEVERE SCOLIOSIS AND THREE RETROPERITONEAL AND PELVIC
COMPRESSION SYNDROMES (RPCS) by W. Sandmann , K. Verginis, S. Jacobi, and T. Scholbach
PixelFlux makes the antihypertensive treatment effect on renal perfusion measurable
PixelFlux directly demonstrating influence of thyroid hormone level on renal blood flow
2021 12 14
New paper published underscoring the usefulness of PixelFlux measurements in malignant diseases of the pancreas
2021 11 26
Multiple severe compression syndromes and post-operative vomiting and pain – the necessity of a postop PixelFlux exam of all relevant organs
2021 11 07
We published (on the 124. birthday of my grandfather Max Scholbach :-)):
REVIEW ARTICLE
Papers authored by others: by clicking this button I declare the only non-commercial use of this download
2021 10 22
A left renal vein stent – reducing one compression – creating three new ones
2021 09 11
Bending of a straight vein compels its narrowing
English version : Lordosis /hollow back – cause of numerous abdominal compression syndromes.
Muscle cramps caused by a posture dependent pubic compression of the femoral artery
Update: Ehlers Danlos-syndrome the flashing redlight of vascular compressions
2021 08 20
I linked the audio version of my talk ” The Nutcracker syndrome is a misnomer ” to the following page
The Nutcracker Syndrome is a misnomer Euroson September 2018
An audio version of this talk can be found her
2021 08 18
Outline of my special examination technique for patients with connective tissue disorders -see last part of the English version of
Ehlers Danlos-syndrome the flashing redlight of vascular compressions
2021 07 16
Swollen bluish feet nausea unbearable epigastric and breast pain breathlessness
Unbearable breast pain while sitting
2021 06 14
2021 02 05
Why I prefer not to publish in journals but in the Internet
Vessel stretching in nephroptosis – an important driver of complaints2023 01 09
An important paper on headaches as a patient’s only symptom that could be traced back to left renal vein compression was published recently. To my great joy this work was stimulated by my paper “From the nutcracker-phenomenon of the left renal vein to the midline congestion syndrome as a cause of migraine, headache, back and abdominal pain and functional disorders of pelvic organs” :
2022 11 03
2022 09 23
causing right sided back pain and pain in the right upper or mid-abdomen
Diaphragmatic compression of the hepatic veins – a novel compression syndrome
causing intermittent swelling of the liver, fullness and pain in the right upper abdomen
2022 09 11
List of genital symptoms in compression syndromes inserted in “Checklist”
2022 05 09
PixelFlux is recommended in diagnosis of Carpal Tunnel syndrome
chart from the above mentioned paper; inset by Thomas Scholbach
The authors refer to a very positive review of PixelFlux in the World Journal of Radiology 2020
” Interestingly, in the haemodialysis cohort, blood flow measurements were significantly improved after dialysis, suggesting that this measure may have future utility as a biomarker of both disease severity and treatment response[50]. Carroll AS, Simon NG. Current and future applications of ultrasound imaging in peripheral nerve disorders. World J Radiol 2020; 12(6): 101-129 [PMID: 32742576 DOI: 10.4329/wjr.v12.i6.101]”
2022 05 05
Project “International scholarship for quantitative functional color Doppler ultrasound training”
2022 04 10
Example of failed renal autotransplantation in left renal vein compression – the reasons why
2022 04 02
Addition to Wilkie syndrome page with example videos of patients with apparent duodenal compression that can be confidently classified as normal findings by functional sonography
2022 02 19
I now offer my papers for download for personal non-commercial use
Papers authored by others: by clicking this button I declare the only non-commercial use of this download
2022 02 15 (On occasion of the 88th birthday – 15.02.1934 – of my mother
Dr. med. Lilli Scholbach – ophthalmologist til her 75th birthday)
PixelFlux discriminates diabetic neuropathy in patients with chronic renal failure
Peripheral nerve morphology and intraneural blood flow in chronic kidney disease with and without diabetes
T Issar, S Walker, R Arnold, AM Poynten, ZH Endre… – Muscle & Nerve
2022 01 20 ( On occasion of the 39th birthday of my son Prof. Dr. rer. nat. Jakob Scholbach, developer of PixelFlux-software)
Under false flag – the so-called nutcracker syndrome Journal: Vascular Surgery
2022 01 04
Massive hematuria never in the morning but always in the evening – only PixelFlux knows the answer
2022 01 01 ( for the birthday of my great-grandfather Traugott Scholbach 01.01.1866 – 31.05.1942)
I added a search line on the top of all webpages – hoping to provide you more focused information from the dispersed and steadily growing content 🙂
2021 12 29
PixelFlux demonstrates rapid post-dialysis improvement of peripheral nerve perfusion ( BORIRE et al. Prince of Wales Clinical School, University of New South Wales, Sydney, Australia) :
“… we have shown that peripheral nerve hypervascularity is demonstrable in ESKD patients and rapidly improves following a single session of dialysis. Increased INBF is more likely to be seen in nerves of patients with evidence of axonal loss and moderate to severe neuropathy, suggesting that it may be a potential marker of neuropathy severity.
PixelFlux has significantly higher intra- and interobserver reliability than traditional methods to evaluate intraneural blood flow in carpal tunnel syndrome ( BORIRE et al. Prince of Wales Clinical School, University of New South Wales, Sydney, Australia)
PixelFlux perfusion measurements in peripheral diabetic nerves correlate significantly with the severity of diabetic neuropathy ( BORIRE et al. Prince of Wales Clinical School, University of New South Wales, Sydney, Australia)
2021 12 28
THE SURPRISING FREQUENCY OF HYPERMOBILE EHLERS-DANLOS (hEDS) AMONG PATIENTS WITH ABDOMINAL AND PELVIC COMPRESSION SYNDROMES (APCS) by W. Sandmann , K. Verginis, S. Jacobi, and T. Scholbach
Hyper-elastic fibrous tissue disorder is a risk factor for development of multiple retroperitoneal and pelvic compression syndromes and for recurrences after surgery by W. Sandmann , K. Verginis, S. Jacobi, and T. Scholbach
EDS COMPLICATED BY SEVERE SCOLIOSIS AND THREE RETROPERITONEAL AND PELVIC
COMPRESSION SYNDROMES (RPCS) by W. Sandmann , K. Verginis, S. Jacobi, and T. Scholbach
PixelFlux makes the antihypertensive treatment effect on renal perfusion measurable
PixelFlux directly demonstrating influence of thyroid hormone level on renal blood flow
2021 12 14
New paper published underscoring the usefulness of PixelFlux measurements in malignant diseases of the pancreas
2021 11 26
Multiple severe compression syndromes and post-operative vomiting and pain – the necessity of a postop PixelFlux exam of all relevant organs
2021 11 07
We published (on the 124. birthday of my grandfather Max Scholbach :-)):
REVIEW ARTICLE
Papers authored by others: by clicking this button I declare the only non-commercial use of this download
2021 10 22
A left renal vein stent – reducing one compression – creating three new ones
2021 09 11
Bending of a straight vein compels its narrowing
English version : Lordosis /hollow back – cause of numerous abdominal compression syndromes.
Muscle cramps caused by a posture dependent pubic compression of the femoral artery
Update: Ehlers Danlos-syndrome the flashing redlight of vascular compressions
2021 08 20
I linked the audio version of my talk ” The Nutcracker syndrome is a misnomer ” to the following page
The Nutcracker Syndrome is a misnomer Euroson September 2018
An audio version of this talk can be found her
2021 08 18
Outline of my special examination technique for patients with connective tissue disorders -see last part of the English version of
Ehlers Danlos-syndrome the flashing redlight of vascular compressions
2021 07 16
Swollen bluish feet nausea unbearable epigastric and breast pain breathlessness
Unbearable breast pain while sitting
2021 06 14
2021 02 05
Why I prefer not to publish in journals but in the Internet
Vessel stretching in nephroptosis – an important driver of complaints
